GRAIL 2026 is the eighth international Workshop on GRaphs in biomedicAl Image anaLysis,
organized as an in-person satellite event of MICCAI 2026.
Building on the successful joint format of last year, GRAIL continues as a unified forum for graph-based,
higher-order, and topology-informed methods in biomedical image analysis and related domains.
Graphs provide a flexible and scalable mathematical framework for modeling complex, unstructured data,
objects, and their interactions in an interpretable and mathematically grounded way. They underpin a wide
range of methods such as spectral analysis, dimensionality reduction, and network analysis. Since 2017,
geometric deep learning has tightly integrated graph signal processing with deep neural architectures,
leading to rapid progress across medical imaging, shape analysis, brain connectomics, population modeling,
patient multi-omics, and drug discovery. In parallel, graph-based learning has become a major research
direction at leading machine learning and computer vision venues such as CVPR, ICLR, NeurIPS, and the
Learning on Graphs (LoG) conference.
Since its inception in 2017, GRAIL has served as a focused venue within MICCAI for connecting methodological
advances in graph learning with clinically and biologically relevant applications. In 2025, GRAIL broadened
its scope through a collaborative format with
Topology-Guided Imaging (TGI)
and
Hypergraphs in MedIA (HGMIA),
reflecting strong community interest in a shared forum covering graphs, higher-order structures, and topology-inspired methods.
For 2026, GRAIL continues this inclusive direction, with TGI co-organizers from last year joining as co-chairs.
GRAIL 2026 is designed as a compact, half-day workshop featuring invited keynote talks and peer-reviewed
paper presentations. The workshop emphasizes scientific depth, methodological rigor, and strong application
grounding, while fostering exchange between complementary perspectives in graph learning and topological
methods. We also plan to video-record the sessions and make them publicly available after the conference.
Scientific Tracks
Track 1: Graphs and Applications
This track focuses on graph representations and learning methods based on pairwise relationships, as well as
their applications to biomedical image analysis and related data modalities.
- Graph analytics and machine/deep learning on graphs
- Graph neural networks (GNNs) for biomedical image and data analysis
- Signal processing on graphs, including non-learning-based approaches
- Probabilistic graphical models for biomedical data
- Graph generative models
- Graph foundation models and integration with non-graph foundation models
- Graph datasets, benchmarks, and evaluation methodologies
- Learning on small or limited biomedical datasets
- Statistical testing and group-level analysis on graph structures
- Explainable AI (XAI) for graph-based and geometric deep learning
- Inductive biases, symmetry, and equivariance in graph-based models
- Combinations with other paradigms such as self-supervised or federated learning
Track 2: Higher-Order Topologies and Applications
This track highlights methods that go beyond pairwise graph structures by incorporating higher-order
relationships and topological priors.
- Hypergraphs, multiview graphs, multiplex graphs, and PolyConnect structures
- Topological deep learning (TDL) and topological signal processing
- Persistent homology and topology-aware learning methods
- Higher-order representations for biomedical images and multimodal data
- Integration of topology-based methods with deep learning architectures
- Theoretical foundations and practical applications of higher-order relational learning in medicine
Applications covered include but are not limited to:
- Image segmentation, registration, classification
- Graph representations in pathology imaging and whole-slide image analysis
- Graph-based approaches for intra-operative surgical support
- Graph-based shape modeling and dimensionality reduction
- Graphs for large-scale patient population analyses
- Combining multimodal/multi-omics data through graph structures
- Graph analysis of brain networks and connectomics
Through this structure, GRAIL 2026 aims to continue serving as a unifying forum for graph-based and
topology-informed research in biomedical image analysis, reflecting both the evolution of the field and the
interests of the broader MICCAI community.